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BRCT domain : ウィキペディア英語版
BRCT domain


BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins.

The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage, for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain.
== Examples ==

Human proteins containing this domain include:
* BARD1; BRCA1
* CTDP1; DNTT
* ECT2
* LIG4
* MCPH1; MDC1
* NBN
* PARP1; PARP4; PAXIP1; PES1
* REV1; RFC1; TOPBP1; TP53BP1; XRCC1

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「BRCT domain」の詳細全文を読む



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